Gene: Sh2b1 ENSRNOG00000049181

Description

SH2B adaptor protein 1 [Source:RGD Symbol;Acc:620132]

Gene Synonyms

Sh2-b, Sh2b, Sh2bpsm1

Location

GRCr8:CM070391.1

About this gene

This gene has 2 transcripts (splice variants), 187 orthologues, 2 paralogues and is associated with 8 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000074274.4	Sh2b1-202	3338	724aa	ENSRNOP00000066048.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8L2QYJ5 A6I963	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000071241.5	Sh2b1-201	3166	682aa	ENSRNOP00000064854.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A6I970 M0R617	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,