Summary
- Splice variants
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Sequence
- Secondary Structure
Comparative Genomics
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Phenotypes
Genetic Variation
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Pathway
Molecular interactions
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Gene: Icos ENSRNOG00000046196

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Description

inducible T-cell co-stimulator [Source:RGD Symbol;Acc:620123]

Location

Primary_assembly 9: 69,877,785-69,900,960 forward strand.

GRCr8:CM070399.1

About this gene

This gene has 4 transcripts (splice variants), 115 orthologues and is associated with 17 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000119869.2	Icos-203	717	222aa	ENSRNOP00000079452.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I5ZN49	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000071226.4	Icos-201	2050	200aa	ENSRNOP00000064455.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	Q9R1T7-1	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000156653.1	Icos-204	909	207aa	ENSRNOP00000099767.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	-
ENSRNOT00000091060.3	Icos-202	675	208aa	ENSRNOP00000070990.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A0G2JZC0	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,

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Strains

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Genomic alignments

Gene tree

Orthologues

Paralogues (Not available)

Families (Not available)

More views of comparative genomics data, such as multiple alignments and synteny, are available on the Location page for this gene.

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Personal Data