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Gene: Mgmt ENSRNOG00000016038

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Description

O-6-methylguanine-DNA methyltransferase [Source:RGD Symbol;Acc:3087]

Location

Primary_assembly 1: 201,140,661-201,367,482 forward strand.

GRCr8:CM070391.1

About this gene

This gene has 3 transcripts (splice variants), 190 orthologues and is associated with 31 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000021537.6	Mgmt-201	865	254aa	ENSRNOP00000021537.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8L2QAS3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000119456.2	Mgmt-203	850	209aa	ENSRNOP00000079311.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A6HX75 P24528	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000093786.2	Mgmt-202	837	244aa	ENSRNOP00000084903.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6GB83	-

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Strains

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Genomic alignments

Gene tree

Orthologues

Paralogues (Not available)

Families (Not available)

More views of comparative genomics data, such as multiple alignments and synteny, are available on the Location page for this gene.

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Personal Data