Gene: Irs1 ENSRNOG00000014597

Description

insulin receptor substrate 1 [Source:RGD Symbol;Acc:2922]

Gene Synonyms

IRS-1, IRS1IRM, pp185

Location

GRCr8:CM070399.1

About this gene

This gene has 2 transcripts (splice variants), 136 orthologues, 3 paralogues and is associated with 24 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000144395.1	Irs1-202	13538	1235aa	ENSRNOP00000101528.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A6JW94	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical,
ENSRNOT00000019579.7	Irs1-201	9346	1235aa	ENSRNOP00000019579.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A6JW94 G3V7V7	APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,

Strains

More views of comparative genomics data, such as multiple alignments and synteny, are available on the Location page for this gene.