Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: Nrg1 ENSRNOG00000010392

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Description

neuregulin 1 [Source:RGD Symbol;Acc:621341]

Location

Primary_assembly 16: 65,953,865-66,999,849 forward strand.

GRCr8:CM070406.1

About this gene

This gene has 9 transcripts (splice variants), 206 orthologues, 3 paralogues and is associated with 70 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000058727.6	Nrg1-205	3559	855aa	ENSRNOP00000055518.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A6IVT9 G3V9Q0	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000013991.10	Nrg1-201	3842	517aa	ENSRNOP00000013991.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	G3V7D6	-
ENSRNOT00000081522.3	Nrg1-206	3715	700aa	ENSRNOP00000072731.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A0G2K3Q3 A6IVV2	-
ENSRNOT00000082355.3	Nrg1-207	3700	695aa	ENSRNOP00000071312.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A0G2K057 A6IVV1	-
ENSRNOT00000014268.10	Nrg1-203	3324	662aa	ENSRNOP00000014268.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A6IVU4 G3V7F0	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000038549.9	Nrg1-204	3310	432aa	ENSRNOP00000031467.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	D3ZC94	-
ENSRNOT00000014147.8	Nrg1-202	3252	638aa	ENSRNOP00000014147.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	D4ACB2	-
ENSRNOT00000100344.2	Nrg1-209	3252	638aa	ENSRNOP00000081913.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I5ZSN5	-
ENSRNOT00000099919.2	Nrg1-208	2946	624aa	ENSRNOP00000077747.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I5ZKD3	-

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Strains

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Genomic alignments

Gene tree

Orthologues

Paralogues

Families (Not available)

More views of comparative genomics data, such as multiple alignments and synteny, are available on the Location page for this gene.

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Personal Data