Gene: Topbp1 ENSRNOG00000009789

Description

DNA topoisomerase II binding protein 1 [Source:RGD Symbol;Acc:1562949]

Gene Synonyms

LOC315969, RGD1562949

Location

GRCr8:CM070398.1

About this gene

This gene has 2 transcripts (splice variants), 199 orthologues, 1 paralogue and is associated with 4 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000109766.2	Topbp1-201	5517	1594aa	ENSRNOP00000096497.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6GM39	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000115411.2	Topbp1-202	5047	1399aa	ENSRNOP00000087421.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6GFZ6	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,