Gene: Mthfr ENSRNOG00000008553

Description

methylenetetrahydrofolate reductase [Source:RGD Symbol;Acc:1309952]

Gene Synonyms

LOC362657

Location

Primary_assembly 5: 163,748,321-163,768,105 forward strand.

GRCr8:CM070395.1

About this gene

This gene has 3 transcripts (splice variants), 206 orthologues, 4 paralogues and is associated with 187 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000102508.2	Mthfr-202	5823	694aa	ENSRNOP00000085916.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6A4C5	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P4: Where the APPRIS core modules are unable to choose a clear principal CDS and there is more than one variant with a distinct (but consecutive) CCDS identifiers, APPRIS selects the longest CCDS isoform as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P4,
ENSRNOT00000118752.2	Mthfr-203	5833	654aa	ENSRNOP00000086290.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6A5Q6 A6IU43	APPRIS ALT1: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that is conserved in at least three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT1,
ENSRNOT00000011384.9	Mthfr-201	5798	660aa	ENSRNOP00000011384.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A6IU40 D4A7E8	-