Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: SIRT2 ENSPTRG00000010945

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Description

sirtuin 2 [Source:VGNC Symbol;Acc:VGNC:12099]

Location

Chromosome 19: 40,893,399-40,914,654 reverse strand.

Pan_tro_3.0:CM000333.3

About this gene

This gene has 6 transcripts (splice variants), 191 orthologues and 7 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSPTRT00000020286.6	SIRT2-201	2067	389aa	ENSPTRP00000018763.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A6D2Y4Q4 K7BWL3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P5: Where the APPRIS core modules are unable to choose a clear principal variant and none of the candidate variants are annotated by CCDS, APPRIS selects the longest of the candidate isoforms as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P5,
ENSPTRT00000087204.1	SIRT2-202	2033	352aa	ENSPTRP00000084325.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3T519 A0A6D2XXV8	APPRIS ALT1: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that is conserved in at least three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT1,
ENSPTRT00000084153.1	SIRT2-203	1107	368aa	ENSPTRP00000071396.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3S384	-
ENSPTRT00000084315.1	SIRT2-204	990	329aa	ENSPTRP00000092305.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3TSU8	-
ENSPTRT00000094365.1	SIRT2-205	705	234aa	ENSPTRP00000085191.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3T7J0 A0A6D2XT79	-
ENSPTRT00000078007.1	SIRT2-206	336	111aa	ENSPTRP00000064213.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3RHV4	-

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Summary

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