Gene: Gsdmd ENSMUSG00000022575

Description

gasdermin D [Source:MGI Symbol;Acc:MGI:1916396]

Gene Synonyms

1810036L03Rik, DF5L, Dfna5l, Gsdmdc1, M2-4

Location

Chromosome 15: 75,734,176-75,739,257 forward strand.

GRCm39:CM001008.3

About this gene

This gene has 6 transcripts (splice variants), 186 orthologues, 8 paralogues and is associated with 8 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000023238.6	Gsdmd-201	1792	487aa	ENSMUSP00000023238.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS27551	A0A679AXP3 Q9D8T2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000229331.2	Gsdmd-202	898	263aa	ENSMUSP00000155802.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A2R8VKQ7	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000230514.2	Gsdmd-203	415	57aa	ENSMUSP00000155766.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A2R8W727	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000230571.2	Gsdmd-204	915	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000231170.2	Gsdmd-206	677	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000230881.2	Gsdmd-205	406	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-

Gene: Gsdmd ENSMUSG00000022575

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Gene: Gsdmd ENSMUSG00000022575

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