Gene: Kmt2d ENSMUSG00000048154

Description

lysine (K)-specific methyltransferase 2D [Source:MGI Symbol;Acc:MGI:2682319]

Gene Synonyms

C430014K11Rik, Mll2, Mll4, bapa

Location

Chromosome 15: 98,729,550-98,769,085 reverse strand.

GRCm39:CM001008.3

About this gene

This gene has 5 transcripts (splice variants), 230 orthologues, 20 paralogues and is associated with 39 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000023741.16	Kmt2d-201	19823	5588aa	ENSMUSP00000023741.9	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS49725	A0A0A0MQ73	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P4: Where the APPRIS core modules are unable to choose a clear principal CDS and there is more than one variant with a distinct (but consecutive) CCDS identifiers, APPRIS selects the longest CCDS isoform as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P4, TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5,
ENSMUST00000178486.9	Kmt2d-202	19805	5588aa	ENSMUSP00000135941.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q6PDK2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2, TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5,
ENSMUST00000191973.3	Kmt2d-204	899	233aa	ENSMUSP00000142312.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A0A6YY77	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENSMUST00000184363.3	Kmt2d-203	751	250aa	ENSMUSP00000139020.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		V9GX77	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENSMUST00000229651.2	Kmt2d-205	470	22aa	ENSMUSP00000154984.2	Nonsense mediated decay		A0A2R8VHD4	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,