Gene: Adamts6 ENSMUSG00000046169

Description

ADAM metallopeptidase with thrombospondin type 1 motif 6 [Source:MGI Symbol;Acc:MGI:1347348]

Gene Synonyms

A930019D11Rik, ADAM-TS6, b2b1879.1Clo, b2b2029Clo, b2b2182Clo, b2b2187.1Clo, b2b2228Clo

Location

Chromosome 13: 104,424,343-104,633,203 forward strand.

GRCm39:CM001006.3

About this gene

This gene has 7 transcripts (splice variants), 210 orthologues, 25 paralogues and is associated with 46 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000224208.2	Adamts6-203	6480	1117aa	ENSMUSP00000153359.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS36773	D3Z1A5	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENSMUST00000065766.7	Adamts6-201	4822	1117aa	ENSMUSP00000064570.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS36773	D3Z1A5	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5,
ENSMUST00000224784.2	Adamts6-207	7690	468aa	ENSMUSP00000153665.2	Nonsense mediated decay		A0A286YEC9	-
ENSMUST00000224742.2	Adamts6-206	4901	292aa	ENSMUSP00000152936.2	Nonsense mediated decay		A0A286YCD8	-
ENSMUST00000224303.2	Adamts6-204	4672	292aa	ENSMUSP00000153431.2	Nonsense mediated decay		A0A286YCD8	-
ENSMUST00000223562.2	Adamts6-202	3840	468aa	ENSMUSP00000153504.2	Nonsense mediated decay		A0A286YEC9	-
ENSMUST00000224504.2	Adamts6-205	745	96aa	ENSMUSP00000153194.2	Nonsense mediated decay		A0A286YCZ1	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,