Gene: Rbbp8 ENSMUSG00000041238

Description

retinoblastoma binding protein 8, endonuclease [Source:MGI Symbol;Acc:MGI:2442995]

Gene Synonyms

9930104E21Rik, CtIP

Location

Chromosome 18: 11,766,333-11,878,278 forward strand.

GRCm39:CM001011.3

About this gene

This gene has 11 transcripts (splice variants), 214 orthologues, 1 paralogue and is associated with 7 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000115861.9	Rbbp8-202	3523	893aa	ENSMUSP00000111527.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS37738	Q80YR6	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000047322.8	Rbbp8-201	3209	893aa	ENSMUSP00000046255.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS37738	Q80YR6	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000234499.2	Rbbp8-206	586	118aa	ENSMUSP00000157079.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A3Q4L2U0	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000234984.2	Rbbp8-210	5471	612aa	ENSMUSP00000157008.2	Nonsense mediated decay		A0A3Q4EGK0	-
ENSMUST00000235039.2	Rbbp8-211	3360	247aa	ENSMUSP00000157244.2	Nonsense mediated decay		A0A3Q4EGL1	-
ENSMUST00000234616.2	Rbbp8-207	781	26aa	ENSMUSP00000157098.2	Nonsense mediated decay		A0A3Q4EBX2	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENSMUST00000234184.2	Rbbp8-205	3714	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000234074.2	Rbbp8-203	1904	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000234766.2	Rbbp8-209	1736	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000234744.2	Rbbp8-208	857	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000234161.2	Rbbp8-204	679	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-