Gene: Smad3 ENSMUSG00000032402

Description

SMAD family member 3 [Source:MGI Symbol;Acc:MGI:1201674]

Gene Synonyms

Madh3, Smad 3

Location

Chromosome 9: 63,554,049-63,665,276 reverse strand.

GRCm39:CM001002.3

About this gene

This gene has 5 transcripts (splice variants), 274 orthologues, 7 paralogues and is associated with 94 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000034973.10	Smad3-201	5090	425aa	ENSMUSP00000034973.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS23272	Q8BUN5	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000154323.8	Smad3-205	744	233aa	ENSMUSP00000116790.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A2CG44	TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000137713.8	Smad3-204	466	113aa	ENSMUSP00000121671.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A2CG45	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000133108.3	Smad3-202	429	143aa	ENSMUSP00000122217.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F7BUP2	TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5, 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENSMUST00000137065.2	Smad3-203	406	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2,

Strains

More views of comparative genomics data, such as multiple alignments and synteny, are available on the Location page for this gene.

Gene: Smad3 ENSMUSG00000032402

Strains

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Gene: Smad3 ENSMUSG00000032402

Strains

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