Gene: Lrp5 ENSMUSG00000024913

Description

low density lipoprotein receptor-related protein 5 [Source:MGI Symbol;Acc:MGI:1278315]

Gene Synonyms

LR3, LRP7

Location

Chromosome 19: 3,634,828-3,736,564 reverse strand.

GRCm39:CM001012.3

About this gene

This gene has 4 transcripts (splice variants), 209 orthologues, 15 paralogues and is associated with 85 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000025856.17	Lrp5-201	5161	1614aa	ENSMUSP00000025856.11	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS37881	Q91VN0-1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000176867.2	Lrp5-202	2759	618aa	ENSMUSP00000135654.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H3BL52	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000177330.8	Lrp5-204	8893	279aa	ENSMUSP00000134983.2	Nonsense mediated decay		H3BJH0	TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2,
ENSMUST00000177294.2	Lrp5-203	2835	226aa	ENSMUSP00000134771.2	Nonsense mediated decay		H3BIY3	TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1, 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,