Gene: Map3k4 ENSMUSG00000014426

Description

mitogen-activated protein kinase kinase kinase 4 [Source:MGI Symbol;Acc:MGI:1346875]

Gene Synonyms

D17Rp17, D17Rp17e, MAPKKK4, MTK1, Mekk4, RP17, T-associated sex reversal, Tas

Location

Chromosome 17: 12,446,508-12,537,683 reverse strand.

GRCm39:CM001010.3

About this gene

This gene has 9 transcripts (splice variants), 147 orthologues, 8 paralogues and is associated with 26 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000089058.7	Map3k4-201	5441	1597aa	ENSMUSP00000086459.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS37435	O08648-1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000233755.2	Map3k4-209	5237	1545aa	ENSMUSP00000156730.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		O08648-2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P4: Where the APPRIS core modules are unable to choose a clear principal CDS and there is more than one variant with a distinct (but consecutive) CCDS identifiers, APPRIS selects the longest CCDS isoform as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P4,
ENSMUST00000233002.2	Map3k4-204	470	96aa	ENSMUSP00000156645.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A3B2W3Y3	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000233012.2	Map3k4-205	406	70aa	ENSMUSP00000156490.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A3B2WCF6	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000233252.2	Map3k4-206	473	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	-
ENSMUST00000232689.2	Map3k4-202	389	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	-
ENSMUST00000233683.2	Map3k4-207	3813	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000232931.2	Map3k4-203	3576	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000233716.2	Map3k4-208	755	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-

Strains

More views of comparative genomics data, such as multiple alignments and synteny, are available on the Location page for this gene.

Gene: Map3k4 ENSMUSG00000014426

Strains

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Gene: Map3k4 ENSMUSG00000014426

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