Gene: Tnk1 ENSMUSG00000001583

Description

tyrosine kinase, non-receptor, 1 [Source:MGI Symbol;Acc:MGI:1930958]

Gene Synonyms

Kos1, Tnk1a, Tnk1b

Location

Chromosome 11: 69,741,831-69,749,556 reverse strand.

GRCm39:CM001004.3

About this gene

This gene has 5 transcripts (splice variants), 87 orthologues, 32 paralogues and is associated with 19 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000108628.8	Tnk1-203	2450	671aa	ENSMUSP00000104268.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5F2B4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P4: Where the APPRIS core modules are unable to choose a clear principal CDS and there is more than one variant with a distinct (but consecutive) CCDS identifiers, APPRIS selects the longest CCDS isoform as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P4, TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5,
ENSMUST00000001626.10	Tnk1-201	2778	666aa	ENSMUSP00000001626.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS24917	Q99ML2-1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000108626.8	Tnk1-202	1798	434aa	ENSMUSP00000104266.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q99ML2-2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000125571.2	Tnk1-204	1021	268aa	ENSMUSP00000118490.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A2ARN2	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000156507.2	Tnk1-205	560	186aa	ENSMUSP00000120585.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5F2B6	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,

Strains

More views of comparative genomics data, such as multiple alignments and synteny, are available on the Location page for this gene.

Gene: Tnk1 ENSMUSG00000001583

Strains

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Gene: Tnk1 ENSMUSG00000001583

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