Gene: Espl1 ENSMUSG00000058290

Description

extra spindle pole bodies 1, separase [Source:MGI Symbol;Acc:MGI:2146156]

Gene Synonyms

Cerp, ESP1, PRCE, SSE, separase

Location

Chromosome 15: 102,204,701-102,232,792 forward strand.

GRCm39:CM001008.3

About this gene

This gene has 9 transcripts (splice variants), 185 orthologues and is associated with 8 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000064924.6	Espl1-201	6658	2118aa	ENSMUSP00000064465.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS27878	P60330	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000229050.2	Espl1-202	6635	2118aa	ENSMUSP00000155304.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS27878	P60330	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENSMUST00000231104.2	Espl1-208	670	99aa	ENSMUSP00000155469.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A2R8VHV9	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000230212.2	Espl1-205	657	165aa	ENSMUSP00000155074.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A2R8VHG0	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000229942.2	Espl1-203	447	110aa	ENSMUSP00000155666.2	Nonsense mediated decay		A0A2R8VI27	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENSMUST00000230617.2	Espl1-207	2298	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000231207.2	Espl1-209	544	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000230116.2	Espl1-204	434	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000230222.2	Espl1-206	296	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-