Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: Pcx ENSMUSG00000024892

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Description

pyruvate carboxylase [Source:MGI Symbol;Acc:MGI:97520]

Gene Synonyms

Pc

Location

Chromosome 19: 4,560,500-4,671,780 forward strand.

GRCm39:CM001012.3

About this gene

This gene has 7 transcripts (splice variants), 226 orthologues, 4 paralogues and is associated with 12 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000068004.13	Pcx-201	4148	1179aa	ENSMUSP00000063825.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS50352	E9QPD7	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P5: Where the APPRIS core modules are unable to choose a clear principal variant and none of the candidate variants are annotated by CCDS, APPRIS selects the longest of the candidate isoforms as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P5, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000224726.3	Pcx-204	4061	1178aa	ENSMUSP00000153479.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS29430	G5E8R3	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS ALT1: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that is conserved in at least three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT1,
ENSMUST00000113825.4	Pcx-202	4044	1178aa	ENSMUSP00000109456.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS29430	G5E8R3	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS ALT1: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that is conserved in at least three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000225189.3	Pcx-205	595	116aa	ENSMUSP00000152918.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A286YCC5	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000238089.2	Pcx-207	414	120aa	ENSMUSP00000157436.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A494B912	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000236457.2	Pcx-206	393	97aa	ENSMUSP00000157492.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A494B951	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000223659.2	Pcx-203	275	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	-

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Strains

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Genomic alignments

Gene tree

Orthologues

Paralogues

Families (Not available)

More views of comparative genomics data, such as multiple alignments and synteny, are available on the Location page for this gene.

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Personal Data