Gene: Stk3 ENSMUSG00000022329

Description

serine/threonine kinase 3 [Source:MGI Symbol;Acc:MGI:1928487]

Gene Synonyms

0610042I06Rik, MST, Mst2, Ste20, mess1

Location

Chromosome 15: 34,875,642-35,179,067 reverse strand.

GRCm39:CM001008.3

About this gene

This gene has 6 transcripts (splice variants), 214 orthologues, 35 paralogues and is associated with 12 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000018476.14	Stk3-201	2914	497aa	ENSMUSP00000018476.8	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS37059	Q9JI10-1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000226555.2	Stk3-205	2730	495aa	ENSMUSP00000154154.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A2I3BQE0	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENSMUST00000067033.8	Stk3-202	2471	427aa	ENSMUSP00000064225.8	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q9JI10-2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000138841.2	Stk3-204	773	38aa	ENSMUSP00000116310.2	Nonsense mediated decay		D6RHQ9	TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5,
ENSMUST00000226730.2	Stk3-206	3294	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000128425.2	Stk3-203	605	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2,