Transcript: ENST00000377365.4 INSYN2B-201

Description

inhibitory synaptic factor family member 2B [Source:HGNC Symbol;Acc:HGNC:37271]

Gene Synonyms

C5ORF57, FAM196B

Location

Chromosome 5: 169,861,303-169,980,495 reverse strand.

About this transcript

This transcript has 4 exons, is annotated with 18 domains and features, is associated with 49500 variant alleles and maps to 345 oligo probes.

Gene

This transcript is a product of gene ENSG00000204767.4 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000377365.4	INSYN2B-201	5715	535aa	ENSP00000366582.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS47336	A6NMK8	NM_001129891.3	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2,
ENST00000523970.1	INSYN2B-202	595	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	-	TSL 4: A transcript where the best supporting EST is flagged as suspect The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:4,

Summary

Statistics

Exons: 4, Coding exons: 3, Transcript length: 5,715 bps, Translation length: 535 residues

MANE

This MANE Select transcript contains ENSP00000366582 and matches to NM_001129891.3 and NP_001123363.1

Uniprot

This transcript corresponds to the following Uniprot identifiers: A6NMK8

CCDS

This transcript is a member of the Human CCDS set: CCDS47336

Transcript Support Level (TSL)

TSL:2

Version

ENST00000377365.4

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

GENCODE primary gene

This transcript is a member of the Gencode Primary gene set.

Transcript: ENST00000377365.4 INSYN2B-201

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Transcript: ENST00000377365.4 INSYN2B-201

Summary

About Us

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