Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: irs1 ENSDARG00000054087

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Description

insulin receptor substrate 1 [Source:HGNC Symbol;Acc:HGNC:6125]

Location

Chromosome 15: 35,888,549-35,930,070 reverse strand.

GRCz11:CM002899.2

About this gene

This gene has 1 transcript (splice variant), 136 orthologues, 5 paralogues and is associated with 3 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSDART00000076229.5	irs1-201	8274	1099aa	ENSDARP00000070706.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	E7F4P8	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,

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Summary

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