Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Molecular function
- GO: Cellular component
- GO: Biological process
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: top1a ENSDARG00000070545

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Description

DNA topoisomerase Ia [Source:ZFIN;Acc:ZDB-GENE-060616-217]

Location

Chromosome 11: 25,296,366-25,311,677 forward strand.

GRCz11:CM002895.2

About this gene

This gene has 3 transcripts (splice variants), 206 orthologues and 3 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSDART00000065949.8	top1a-201	3795	758aa	ENSDARP00000065948.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	Q1ED17	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENSDART00000162149.2	top1a-203	759	94aa	ENSDARP00000139289.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENSDART00000122249.3	top1a-202	580	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript	-	-

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Summary

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