Gene: tph2 ENSDARG00000057239

Description

tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) [Source:NCBI gene (formerly Entrezgene);Acc:407712]

Gene Synonyms

tphR, wu:fq15a04

Location

GRCz11:CM002902.2

About this gene

This gene has 2 transcripts (splice variants), 200 orthologues, 5 paralogues and is associated with 14 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSDART00000079832.6	tph2-201	2010	500aa	ENSDARP00000074283.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSDART00000112627.5	tph2-202	2216	473aa	ENSDARP00000102919.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	Q1LUE3	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,

Summary