Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
- Genomic alignments
- Gene tree
- Gene gain/loss tree
- Orthologues
- Paralogues
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: FTO ENSDARG00000044216

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Description

FTO alpha-ketoglutarate dependent dioxygenase [Source:HGNC Symbol;Acc:HGNC:24678]

Location

Chromosome 7: 36,110,972-36,358,735 reverse strand.

GRCz11:CM002891.2

About this gene

This gene has 3 transcripts (splice variants), 203 orthologues and is associated with 21 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSDART00000130028.4	FTO-201	3353	567aa	ENSDARP00000107656.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSDART00000188392.1	FTO-203	4295	580aa	ENSDARP00000145984.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8M9PKY4	APPRIS P5: Where the APPRIS core modules are unable to choose a clear principal variant and none of the candidate variants are annotated by CCDS, APPRIS selects the longest of the candidate isoforms as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P5,
ENSDART00000064913.6	FTO-202	851	50aa	ENSDARP00000064912.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,

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Summary

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