Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
- Genomic alignments
- Gene tree
- Gene gain/loss tree
- Orthologues
- Paralogues
- Breeds
  - Gene tree
  - Orthologues
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Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: DOT1L ENSBTAG00000009996

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Description

DOT1 like histone lysine methyltransferase [Source:VGNC Symbol;Acc:VGNC:50607]

Location

Primary_assembly 7: 21,334,591-21,386,649 forward strand.

ARS-UCD2.0:CM008174.2

About this gene

This gene has 5 transcripts (splice variants) and 203 orthologues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSBTAT00000094220.2	DOT1L-202	5402	1714aa	ENSBTAP00000098485.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9SAE1 A0AAA9TJ61	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSBTAT00000013182.8	DOT1L-203	5339	1693aa	ENSBTAP00000013182.8	Gene/transcipt that contains an open reading frame (ORF).Protein coding	E1BGK8	-
ENSBTAT00000091317.2	DOT1L-201	5321	1593aa	ENSBTAP00000100864.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9TW72	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSBTAT00000099583.2	DOT1L-205	4982	1524aa	ENSBTAP00000102718.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9U0S8	-
ENSBTAT00000082174.3	DOT1L-204	4973	1521aa	ENSBTAP00000065258.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A3Q1LX03	-

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Summary

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