Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: CASP8 ENSBTAG00000015718

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Description

caspase 8 [Source:VGNC Symbol;Acc:VGNC:26784]

Location

Primary_assembly 2: 89,861,777-89,885,542 forward strand.

ARS-UCD2.0:CM008169.2

About this gene

This gene has 3 transcripts (splice variants), 131 orthologues and 12 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSBTAT00000038313.5	CASP8-201	2755	485aa	ENSBTAP00000038128.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	Q2LGB8	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSBTAT00000075852.3	CASP8-202	2689	463aa	ENSBTAP00000062824.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A3Q1N1D1	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSBTAT00000110051.2	CASP8-203	2485	395aa	ENSBTAP00000082117.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9S9Y3	-

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Summary

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