Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: IRS1 ENSBTAG00000021308

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Description

insulin receptor substrate 1 [Source:VGNC Symbol;Acc:VGNC:30283]

Location

Primary_assembly 2: 114,900,806-114,993,635 reverse strand.

ARS-UCD2.0:CM008169.2

About this gene

This gene has 5 transcripts (splice variants), 136 orthologues and 2 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSBTAT00000099636.1	IRS1-203	14030	1237aa	ENSBTAP00000075009.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F1MYE0	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENSBTAT00000117888.1	IRS1-204	13241	1237aa	ENSBTAP00000091525.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F1MYE0	APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENSBTAT00000129242.1	IRS1-201	8189	1237aa	ENSBTAP00000082854.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F1MYE0	APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENSBTAT00000101673.1	IRS1-202	8077	1237aa	ENSBTAP00000076736.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F1MYE0	APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENSBTAT00000028392.6	IRS1-205	5687	1237aa	ENSBTAP00000028392.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F1MYE0	APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,

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Summary

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