Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: PSEN1 ENSBTAG00000011757

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Description

presenilin 1 [Source:VGNC Symbol;Acc:VGNC:33434]

Location

Primary_assembly 10: 84,619,547-84,686,874 forward strand.

ARS-UCD2.0:CM008177.2

About this gene

This gene has 5 transcripts (splice variants), 200 orthologues and 1 paralogue.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSBTAT00000068561.3	PSEN1-203	2864	477aa	ENSBTAP00000057240.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAF6ZSR9	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical,
ENSBTAT00000015615.7	PSEN1-202	2802	474aa	ENSBTAP00000015615.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAF6ZE42 F6RMU4	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSBTAT00000097227.2	PSEN1-204	2738	435aa	ENSBTAP00000082301.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9SIC4	-
ENSBTAT00000131114.2	PSEN1-205	2663	410aa	ENSBTAP00000086997.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9SKW1	-
ENSBTAT00000086321.2	PSEN1-201	2629	458aa	ENSBTAP00000069430.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A3Q1MEI7	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,

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Summary

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