Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: PTEN ENSBTAG00000009498

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Description

phosphatase and tensin homolog [Source:VGNC Symbol;Acc:VGNC:33496]

Location

Primary_assembly 26: 9,420,093-9,567,480 forward strand.

ARS-UCD2.0:CM008193.2

About this gene

This gene has 5 transcripts (splice variants), 139 orthologues and 5 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSBTAT00000012499.8	PTEN-204	5221	573aa	ENSBTAP00000012499.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A024QYS0 F1MDX9	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSBTAT00000144120.1	PTEN-201	4974	429aa	ENSBTAP00000104717.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSBTAT00000083285.3	PTEN-205	4890	388aa	ENSBTAP00000060588.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A3Q1MXQ5	-
ENSBTAT00000154313.1	PTEN-202	4793	369aa	ENSBTAP00000107533.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	-
ENSBTAT00000133981.2	PTEN-203	4752	397aa	ENSBTAP00000102572.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9U0H6	-

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Summary

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