Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: ADAM17 ENSBTAG00000001141

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Description

ADAM metallopeptidase domain 17 [Source:VGNC Symbol;Acc:VGNC:25607]

Location

Primary_assembly 11: 87,917,519-87,961,977 forward strand.

ARS-UCD2.0:CM008178.2

About this gene

This gene has 4 transcripts (splice variants), 279 orthologues and 30 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSBTAT00000120140.2	ADAM17-202	4164	825aa	ENSBTAP00000086325.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9SM15	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSBTAT00000119418.2	ADAM17-203	4074	795aa	ENSBTAP00000079135.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9RZV6	-
ENSBTAT00000118285.2	ADAM17-204	4002	799aa	ENSBTAP00000102839.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9TZW0	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSBTAT00000001519.7	ADAM17-201	1877	549aa	ENSBTAP00000001519.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	E1B867	-

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Summary

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