Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase; required for biosynthesis of isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; also has a role in tRNA gene-mediated silencing; gene encodes two isozymic forms; converts to a prion form, prion conversion contributes to azole antifungal resistance by upregulating ergosterol biosynthesis; homolog of human TRIT1, a mutation in which is associated with severe combined respiratory chain defects [Source:SGD;Acc:S000005800]
Chromosome XV: 837,674-838,960 forward strand.
R64-1-1:BK006948.2
This gene has 1 transcript (splice variant) and 220 orthologues.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YOR274W_mRNA | MOD5 | 1287 | 428aa | YOR274W | Protein coding | P07884 | Ensembl Canonical, |