Description
Largest subunit of the Anaphase-Promoting Complex/Cyclosome; APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the platform domain of the APC/C, based on structural analysis; localizes to nuclear foci that become diffuse upon DNA replication stress [Source:SGD;Acc:S000005116]
Location
Chromosome XIV: 310,636-315,882 forward strand.
R64-1-1:BK006947.3
About this gene
This gene has 1 transcript (splice variant) and 221 orthologues.
Transcripts
