Description
Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins [Source:SGD;Acc:S000004601]
Location
Chromosome XIII: 7,244-8,383 forward strand.
R64-1-1:BK006946.2
About this gene
This gene has 1 transcript (splice variant) and 13 paralogues.
Transcripts
