Description
Regulates transcription of ribosomal protein and biogenesis genes; regulates response to nutrients and stress, G2/M transitions during mitotic cell cycle and DNA-damage response, and modulates cell size; regulated by TORC1 and Mrs6p; sequence of zinc finger, ChIP localization data, and protein-binding microarray (PBM) data, and computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p at others; can form the [ISP+] prion [Source:SGD;Acc:S000004395]
Gene Synonyms
[ISP(+)], [ISP+]
Location
Chromosome XII: 925,568-927,619 forward strand.
R64-1-1:BK006945.2
About this gene
This gene has 1 transcript (splice variant) and 265 orthologues.
Transcripts
