Description
Ribosomal 60S subunit protein L8A; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; L8 binds to Domain I of 25S and 5.8 S rRNAs; mutation results in decreased amounts of free 60S subunits; homologous to mammalian ribosomal protein L7A, no bacterial homolog; RPL8A has a paralog, RPL8B, that arose from the whole genome duplication [Source:SGD;Acc:S000001025]
Gene Synonyms
L4A, L8A, MAK7, YL5, rp6
Location
Chromosome VIII: 35,255-36,025 reverse strand.
R64-1-1:BK006934.2
About this gene
This gene has 1 transcript (splice variant), 771 orthologues and 4 paralogues.
Transcripts
