Hexokinase isoenzyme 2; phosphorylates glucose in cytosol; predominant hexokinase during growth on glucose; represses expression of HXK1, GLK1, induces expression of its own gene; antiapoptotic; phosphorylation/dephosphorylation at Ser14 by kinase Snf1p, phosphatase Glc7p-Reg1p regulates nucleocytoplasmic shuttling of Hxk2p; functions downstream of Sit4p in control of cell cycle, mitochondrial function, oxidative stress resistance, chronological lifespan; has paralog HXK1 [Source:SGD;Acc:S000003222]
HEX1, HKB, SCI2
Chromosome VII: 23,935-25,395 forward strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 273 orthologues and 4 paralogues.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YGL253W_mRNA | HXK2 | 1461 | 486aa | YGL253W | Protein coding | P04807 | Ensembl Canonical, |