Subunit a of the F0 sector of mitochondrial F1F0 ATP synthase; mitochondrially encoded; translation is specifically activated by Atp22p; ATP6 and ATP8 mRNAs are not translated in the absence of the F1 sector of ATPase; mutations in human ortholog MT-ATP6 are associated with neurodegenerative disorders such as Neurogenic Ataxia and Retinitis Pigmentosa (NARP), Leigh syndrome (LS), Charcot-Marie-Tooth (CMT), and ataxia telangiectasia [Source:SGD;Acc:S000007268]
OLI2, OLI4, PHO1
Chromosome Mito: 28,487-29,266 forward strand.
R64-1-1:AJ011856.1
This gene has 1 transcript (splice variant) and 266 orthologues.