thrombopoietin [Source:HGNC Symbol;Acc:HGNC:11795]
MGDF, MPLLG, TPO
Chromosome 3: 184,371,935-184,378,207 reverse strand.
This transcript has 6 exons, is annotated with 26 domains and features, is associated with 2983 variant alleles and maps to 696 oligo probes.
This transcript is a product of gene ENSG00000090534.20 Show transcript tableHide transcript table
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000647395.1 | THPO-205 | 1918 | 353aa | ENSP00000494504.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS3265 | P40225-1 | NM_000460.4 | The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2, |
| ENST00000649095.1 | THPO-207 | 2186 | 493aa | ENSP00000497904.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS93432 | A0A3B3ITS0 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2, |
| ENST00000645603.2 | THPO-204 | 1912 | 493aa | ENSP00000494281.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS93432 | A0A3B3ITS0 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2, |
| ENST00000445696.6 | THPO-202 | 1505 | 349aa | ENSP00000410763.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS54693 | P40225-2 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1, |
| ENST00000421442.2 | THPO-201 | 1132 | 286aa | ENSP00000411704.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS77867 | F8W6L1 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1, |
| ENST00000650229.1 | THPO-208 | 960 | 319aa | ENSP00000497233.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS93431 | Q5FBX8 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000477594.1 | THPO-203 | 248 | 12aa | ENSP00000495689.1 | Nonsense mediated decay | A0A2R8Y734 | - | TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1, 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000648612.1 | THPO-206 | 171 | No protein | - | Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined | - | - | - |