Human (GRCh38.p14)
Description

mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127]

Gene Synonyms

COCA2, FCC2, HNPCC, HNPCC2, MLH-1

Location
About this transcript

This transcript has 20 exons, is annotated with 17 domains and features, is associated with 32659 variant alleles and maps to 727 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000231790.8MLH1-2012494756aaENSP00000231790.3
 
Protein coding
CCDS2663P40692-1 NM_000249.4MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P1TSL:1
ENST00000458205.6MLH1-2162608515aaENSP00000402667.2
 
Protein coding
CCDS54563P40692-2 -GENCODE basicTSL:1
ENST00000674019.1MLH1-2352576515aaENSP00000501081.1
 
Protein coding
CCDS54563P40692-2 -GENCODE basic
ENST00000673673.2MLH1-2242574701aaENSP00000500979.2
 
Protein coding
A0A669KAW3 -GENCODE basic
ENST00000492474.6MLH1-2202572515aaENSP00000518393.1
 
Protein coding
CCDS54563A0A024R2S9 -GENCODE basicTSL:5
ENST00000536378.5MLH1-2212567515aaENSP00000444286.2
 
Protein coding
CCDS54563P40692-2 -GENCODE basicTSL:2
ENST00000429117.6MLH1-2042482658aaENSP00000407019.2
 
Protein coding
CCDS54562C9JZ54 -TSL:4
ENST00000616768.6MLH1-2232447725aaENSP00000480669.3
 
Protein coding
A0A087WX20 -GENCODE basicTSL:2
ENST00000435176.5MLH1-2062428658aaENSP00000402564.1
 
Protein coding
CCDS54562P40692-3 -GENCODE basicTSL:2
ENST00000455445.6MLH1-2122296515aaENSP00000398272.2
 
Protein coding
CCDS54563P40692-2 -GENCODE basicTSL:2
ENST00000456676.7MLH1-2132285687aaENSP00000416687.3
 
Protein coding
H0Y818 -GENCODE basicTSL:1
ENST00000539477.6MLH1-2222280515aaENSP00000443665.1
 
Protein coding
CCDS54563P40692-2 -GENCODE basicTSL:2
ENST00000413740.2MLH1-2032219611aaENSP00000416476.2
 
Protein coding
H0Y806 -GENCODE basicTSL:1
ENST00000441265.6MLH1-2071982327aaENSP00000398392.2
 
Protein coding
E7EUC9 -GENCODE basicTSL:5
ENST00000673715.1MLH1-2271978633aaENSP00000501301.1
 
Protein coding
A0A669KBK2 -GENCODE basic
ENST00000673899.1MLH1-2311712512aaENSP00000501030.1
 
Protein coding
A0A669KB03 -GENCODE basic
ENST00000450420.6MLH1-2101640520aaENSP00000393006.2
 
Protein coding
H0Y4N0 -GENCODE basicTSL:1
ENST00000673947.1MLH1-232269838aaENSP00000501304.1
 
Nonsense mediated decay
F2Z298 --
ENST00000673972.1MLH1-233247338aaENSP00000501281.1
 
Nonsense mediated decay
F2Z298 --
ENST00000432299.6MLH1-205244448aaENSP00000416783.1
 
Nonsense mediated decay
E9PF25 -TSL:1
ENST00000674111.1MLH1-2372403568aaENSP00000501162.1
 
Nonsense mediated decay
A0A669KBB4 --
ENST00000673897.1MLH1-230233838aaENSP00000501109.1
 
Nonsense mediated decay
F2Z298 --
ENST00000447829.6MLH1-2092247143aaENSP00000399329.2
 
Nonsense mediated decay
H0Y5L7 -TSL:1
ENST00000413212.2MLH1-202218336aaENSP00000400844.2
 
Nonsense mediated decay
H0Y5U4 -TSL:5
ENST00000458009.6MLH1-2151349314aaENSP00000411066.2
 
Nonsense mediated decay
H0Y793 -TSL:1
ENST00000457004.5MLH1-21466838aaENSP00000407773.1
 
Nonsense mediated decay
F2Z298 -TSL:3
ENST00000454028.5MLH1-21157038aaENSP00000392649.1
 
Nonsense mediated decay
F2Z298 -TSL:5
ENST00000673990.1MLH1-2341711No protein-
 
Protein coding CDS not defined
---
ENST00000485889.1MLH1-219566No protein-
 
Protein coding CDS not defined
--TSL:5
ENST00000466900.5MLH1-217555No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000674107.1MLH1-2362827No protein-
 
Retained intron
---
ENST00000673889.1MLH1-2291799No protein-
 
Retained intron
---
ENST00000673713.1MLH1-2261586No protein-
 
Retained intron
---
ENST00000673741.1MLH1-2281495No protein-
 
Retained intron
---
ENST00000442249.6MLH1-2081303No protein-
 
Retained intron
--TSL:4
ENST00000476172.6MLH1-2181246No protein-
 
Retained intron
--TSL:3
ENST00000674125.1MLH1-2381167No protein-
 
Retained intron
---
ENST00000673686.1MLH1-2251127No protein-
 
Retained intron
---
Statistics

Exons: 20, Coding exons: 11, Transcript length: 2,608 bps, Translation length: 515 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P40692

CCDS

This transcript is a member of the Human CCDS set: CCDS54563

Transcript Support Level (TSL)

TSL:1

Version

ENST00000458205.6

Type

Protein coding

Annotation Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.