Human (GRCh38.p14)
Description

ERCC excision repair 2, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3434]

Gene Synonyms

EM9, MAG, MGC102762, MGC126218, MGC126219, XPD

Location
About this transcript

This transcript has 23 exons, is annotated with 59 domains and features, is associated with 13930 variant alleles and maps to 1138 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000391945.10ERCC2-2044108760aaENSP00000375809.4
 
Protein coding
CCDS33049P18074-1 NM_000400.4MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P1TSL:1
ENST00000684407.1ERCC2-2184013719aaENSP00000507775.1
 
Protein coding
A0A804HK53 -GENCODE basic
ENST00000391941.6ERCC2-2012871706aaENSP00000375805.2
 
Protein coding
A8MX75 -TSL:1CDS 3' incomplete
ENST00000391944.8ERCC2-2032853829aaENSP00000375808.4
 
Protein coding
E7EVE9 -GENCODE basicTSL:1
ENST00000485403.6ERCC2-2051538405aaENSP00000431229.2
 
Protein coding
CCDS46112P18074-2 -GENCODE basicTSL:1
ENST00000586131.6ERCC2-2061015292aaENSP00000464887.1
 
Protein coding
K7EIT8 -TSL:3CDS 3' incomplete
ENST00000586856.1ERCC2-209690109aaENSP00000466998.1
 
Protein coding
K7ENL1 -TSL:5CDS 3' incomplete
ENST00000684218.1ERCC2-2163989205aaENSP00000507804.1
 
Nonsense mediated decay
A0A804HK75 --
ENST00000684458.1ERCC2-2193979459aaENSP00000508260.1
 
Nonsense mediated decay
A0A804HL97 --
ENST00000682414.1ERCC2-2143110760aaENSP00000507019.1
 
Nonsense mediated decay
CCDS33049P18074-1 --
ENST00000587376.6ERCC2-210823202aaENSP00000465593.1
 
Nonsense mediated decay
K7EKF3 -TSL:5CDS 5' incomplete
ENST00000591309.5ERCC2-212557127aaENSP00000465207.1
 
Nonsense mediated decay
B4E0F6 -TSL:4
ENST00000682508.1ERCC2-2154094No protein-
 
Retained intron
---
ENST00000684468.1ERCC2-2203777No protein-
 
Retained intron
---
ENST00000684264.1ERCC2-2173621No protein-
 
Retained intron
---
ENST00000646507.1ERCC2-2133119No protein-
 
Retained intron
---
ENST00000588652.5ERCC2-2112405No protein-
 
Retained intron
--TSL:2
ENST00000391942.6ERCC2-2021488No protein-
 
Retained intron
--TSL:2
ENST00000586441.1ERCC2-207682No protein-
 
Retained intron
--TSL:5
ENST00000586737.5ERCC2-208481No protein-
 
Retained intron
--TSL:5
Statistics

Exons: 23, Coding exons: 23, Transcript length: 4,108 bps, Translation length: 760 residues

MANE

This MANE Select transcript contains ENSP00000375809 and matches to NM_000400.4 and NP_000391.1

Uniprot

This transcript corresponds to the following Uniprot identifiers: P18074

CCDS

This transcript is a member of the Human CCDS set: CCDS33049

Transcript Support Level (TSL)

TSL:1

Version

ENST00000391945.10

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.