Transcript: ENST00000375167.1 H2AX-201

Description

H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739]

Gene Synonyms

H2AFX

Location

Chromosome 11: 119,093,879-119,095,449 reverse strand.

About this transcript

This transcript has 2 exons, is annotated with 34 domains and features, is associated with 1025 variant alleles and maps to 280 oligo probes.

Gene

This transcript is a product of gene ENSG00000188486.4 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000530167.2	H2AX-202	1592	143aa	ENSP00000434024.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS8410	P16104	NM_002105.3	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL NA: A transcript that was not analysed for TSL. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:NA,
ENST00000375167.1	H2AX-201	1373	143aa	ENSP00000364310.1	Nonsense mediated decay	CCDS8410	P16104	-	TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2,

Summary

Statistics

Exons: 2, Coding exons: 1, Transcript length: 1,373 bps, Translation length: 143 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P16104

CCDS

This transcript is a member of the Human CCDS set: CCDS8410

Transcript Support Level (TSL)

TSL:2

Version

ENST00000375167.1

Type

Nonsense mediated decay

Annotation Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

Transcript: ENST00000375167.1 H2AX-201

Summary

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Transcript: ENST00000375167.1 H2AX-201

Summary

About Us

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