Human (GRCh38.p14)
Description

mitogen-activated protein kinase kinase 4 [Source:HGNC Symbol;Acc:HGNC:6844]

Gene Synonyms

JNKK1, MEK4, MKK4, PRKMK4, SERK1

Location
About this transcript

This transcript has 11 exons, is annotated with 18 domains and features, is associated with 53486 variant alleles and maps to 647 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000353533.10MAP2K4-2013778399aaENSP00000262445.5
 
Protein coding
CCDS11162P45985-1 NM_003010.4MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P2TSL:1
ENST00000415385.7MAP2K4-2023856410aaENSP00000410402.3
 
Protein coding
CCDS62095P45985-2 -GENCODE basicAPPRIS ALT2TSL:2
ENST00000602811.5MAP2K4-215113641aaENSP00000473582.1
 
Nonsense mediated decay
R4GN68 -TSL:5
ENST00000602375.5MAP2K4-212106492aaENSP00000473472.1
 
Nonsense mediated decay
R4GN37 -TSL:5
ENST00000602686.5MAP2K4-21497741aaENSP00000473458.1
 
Nonsense mediated decay
R4GN68 -TSL:5
ENST00000602305.5MAP2K4-21196145aaENSP00000473606.1
 
Nonsense mediated decay
J3QLE2 -TSL:5
ENST00000602537.5MAP2K4-21394841aaENSP00000473511.1
 
Nonsense mediated decay
R4GN68 -TSL:5
ENST00000538465.7MAP2K4-20492516aaENSP00000467239.1
 
Nonsense mediated decay
K7EP58 -TSL:5CDS 5' incomplete
ENST00000582183.5MAP2K4-20755145aaENSP00000463507.1
 
Nonsense mediated decay
J3QLE2 -TSL:4
ENST00000581941.5MAP2K4-206813No protein-
 
Protein coding CDS not defined
--TSL:3
ENST00000579089.5MAP2K4-205571No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000582897.5MAP2K4-209482No protein-
 
Protein coding CDS not defined
--TSL:5
ENST00000536413.2MAP2K4-2033852No protein-
 
Retained intron
--TSL:2
ENST00000582377.1MAP2K4-208648No protein-
 
Retained intron
--TSL:3
ENST00000585076.1MAP2K4-210543No protein-
 
Retained intron
--TSL:4
Statistics

Exons: 11, Coding exons: 11, Transcript length: 3,778 bps, Translation length: 399 residues

MANE

This MANE Select transcript contains ENSP00000262445 and matches to NM_003010.4 and NP_003001.1

Uniprot

This transcript corresponds to the following Uniprot identifiers: P45985

CCDS

This transcript is a member of the Human CCDS set: CCDS11162

Transcript Support Level (TSL)

TSL:1

Version

ENST00000353533.10

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.