Transcript: ENST00000335678.7 GRK1-201

Description

G protein-coupled receptor kinase 1 [Source:HGNC Symbol;Acc:HGNC:10013]

Gene Synonyms

GPRK1, RHOK, RK

Location

Chromosome 13: 113,667,219-113,737,736 forward strand.

About this transcript

This transcript has 7 exons, is annotated with 30 domains and features, is associated with 13435 variant alleles and maps to 350 oligo probes.

Gene

This transcript is a product of gene ENSG00000185974.7 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000335678.7	GRK1-201	4233	563aa	ENSP00000334876.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS81785	Q15835	NM_002929.3	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENST00000545304.1	GRK1-202	548	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	-	TSL 4: A transcript where the best supporting EST is flagged as suspect The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:4,
ENST00000606140.1	GRK1-203	3261	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	TSL NA: A transcript that was not analysed for TSL. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:NA,

Summary

Statistics

Exons: 7, Coding exons: 7, Transcript length: 4,233 bps, Translation length: 563 residues

MANE

This MANE Select transcript contains ENSP00000334876 and matches to NM_002929.3 and NP_002920.1

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q15835

CCDS

This transcript is a member of the Human CCDS set: CCDS81785

Transcript Support Level (TSL)

TSL:1

Version

ENST00000335678.7

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript: ENST00000335678.7 GRK1-201

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Transcript: ENST00000335678.7 GRK1-201

Summary

About Us

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