Transcript: ENST00000268638.10 IRF8-201

Description

interferon regulatory factor 8 [Source:HGNC Symbol;Acc:HGNC:5358]

Gene Synonyms

ICSBP, ICSBP1, IRF-8

Location

Chromosome 16: 85,899,162-85,922,606 forward strand.

About this transcript

This transcript has 9 exons, is annotated with 17 domains and features, is associated with 13356 variant alleles and maps to 420 oligo probes.

Gene

This transcript is a product of gene ENSG00000140968.12 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000268638.10	IRF8-201	2668	426aa	ENSP00000268638.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS10956	Q02556	NM_002163.4	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENST00000569607.2	IRF8-210	2693	222aa	ENSP00000456395.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS86547	H3BRT4	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3,
ENST00000564803.6	IRF8-206	2670	426aa	ENSP00000456992.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS10956	H3BT31 Q02556	-	APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2,
ENST00000696887.1	IRF8-215	2624	426aa	ENSP00000512953.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS10956	Q02556	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENST00000566369.2	IRF8-208	2068	209aa	ENSP00000455048.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H3BNX4	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3,
ENST00000563180.1	IRF8-203	1394	126aa	ENSP00000458047.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H3BVC2	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENST00000562492.5	IRF8-202	946	222aa	ENSP00000455452.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS86547	H3BRT4	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3,
ENST00000564617.5	IRF8-205	531	159aa	ENSP00000455784.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H3BQH6	-	TSL 4: A transcript where the best supporting EST is flagged as suspect The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:4, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000565552.1	IRF8-207	522	47aa	ENSP00000455816.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H3BQK3	-	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000569145.5	IRF8-209	289	20aa	ENSP00000455760.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H3BQF9	-	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000696885.1	IRF8-213	3526	130aa	ENSP00000512952.1	Nonsense mediated decay		A0A8Q3SJ00	-	-
ENST00000696884.1	IRF8-212	2608	153aa	ENSP00000512951.1	Nonsense mediated decay		A0A8Q3SJ42	-	-
ENST00000696890.1	IRF8-218	2552	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	-	-
ENST00000696888.1	IRF8-216	1038	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	-	-
ENST00000696889.1	IRF8-217	782	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	-	-
ENST00000696886.1	IRF8-214	4742	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000570088.1	IRF8-211	553	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	TSL 4: A transcript where the best supporting EST is flagged as suspect The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:4,
ENST00000564056.1	IRF8-204	514	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3,

Summary

Statistics

Exons: 9, Coding exons: 8, Transcript length: 2,668 bps, Translation length: 426 residues

MANE

This MANE Select transcript contains ENSP00000268638 and matches to NM_002163.4 and NP_002154.1

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q02556

CCDS

This transcript is a member of the Human CCDS set: CCDS10956

Transcript Support Level (TSL)

TSL:1

Version

ENST00000268638.10

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript: ENST00000268638.10 IRF8-201

Summary

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Transcript: ENST00000268638.10 IRF8-201

Summary

About Us

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