Human (GRCh38.p14)
Description

DNA topoisomerase II binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17008]

Gene Synonyms

DPB11, KIAA0259, TOP2BP1

About this transcript

This transcript has 28 exons, is annotated with 78 domains and features, is associated with 25184 variant alleles and maps to 1132 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000260810.10TOPBP1-20157611522aaENSP00000260810.5
 
Protein coding
CCDS46919Q92547 NM_007027.4MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P4TSL:1
ENST00000642236.1TOPBP1-21061521517aaENSP00000493612.1
 
Protein coding
CCDS87136A0A2R8YD63 -GENCODE basicAPPRIS ALT2
ENST00000572787.1TOPBP1-20940250aaENSP00000458790.1
 
Nonsense mediated decay
I3L1F2 -TSL:4CDS 5' incomplete
ENST00000511439.5TOPBP1-2071142No protein-
 
Protein coding CDS not defined
--TSL:5
ENST00000503338.5TOPBP1-202618No protein-
 
Protein coding CDS not defined
--TSL:3
ENST00000503464.1TOPBP1-203525No protein-
 
Protein coding CDS not defined
--TSL:2
ENST00000513818.1TOPBP1-208898No protein-
 
Retained intron
--TSL:1
ENST00000509162.1TOPBP1-206811No protein-
 
Retained intron
--TSL:2
ENST00000506779.1TOPBP1-205536No protein-
 
Retained intron
--TSL:2
ENST00000505804.1TOPBP1-204472No protein-
 
Retained intron
--TSL:2
Statistics

Exons: 28, Coding exons: 27, Transcript length: 5,761 bps, Translation length: 1,522 residues

MANE

This MANE Select transcript contains ENSP00000260810 and matches to NM_007027.4 and NP_008958.2

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q92547

CCDS

This transcript is a member of the Human CCDS set: CCDS46919

Transcript Support Level (TSL)

TSL:1

Version

ENST00000260810.10

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.