Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: KRAS ENSPTRG00000004775

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Description

KRAS proto-onco, GTPase [Source:VGNC Symbol;Acc:VGNC:10375]

Location

Chromosome 12: 65,619,387-65,665,034 forward strand.

Pan_tro_3.0:CM000326.3

About this gene

This gene has 4 transcripts (splice variants), 201 orthologues and 43 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSPTRT00000101699.1	KRAS-201	5482	189aa	ENSPTRP00000084588.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3T6U4 A0A6D2WV88	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P5: Where the APPRIS core modules are unable to choose a clear principal variant and none of the candidate variants are annotated by CCDS, APPRIS selects the longest of the candidate isoforms as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P5,
ENSPTRT00000008819.4	KRAS-202	5315	188aa	ENSPTRP00000008149.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A6D2X9U3 H2Q5M0	APPRIS ALT1: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that is conserved in at least three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT1,
ENSPTRT00000082725.1	KRAS-204	228	75aa	ENSPTRP00000081336.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3SWK9 A0A6D2XL26	-
ENSPTRT00000090733.1	KRAS-203	132	43aa	ENSPTRP00000074689.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3SCV2 A0A6D2X9J7	-

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Summary

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