Human (GRCh38.p14)
Description

mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840]

Gene Synonyms

MAPKK1, MEK1, PRKMK1

Location

Chromosome 15: 66,386,837-66,491,656 forward strand.

GRCh38:CM000677.2

About this gene

This gene has 17 transcripts (splice variants), 201 orthologues, 8 paralogues and is associated with 67 phenotypes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000307102.10MAP2K1-2012547393aaENSP00000302486.5
 
Protein coding
CCDS10216Q02750-1 NM_002755.4MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P1TSL:1
ENST00000689951.1MAP2K1-2112710410aaENSP00000509308.1
 
Protein coding
A0A8I5KRX5 -GENCODE basic
ENST00000685763.1MAP2K1-2062512344aaENSP00000509016.1
 
Protein coding
A0A8I5KXN4 -GENCODE basic
ENST00000691937.1MAP2K1-2142445317aaENSP00000508768.1
 
Protein coding
A0A8I5QJ96 -GENCODE basic
ENST00000691576.1MAP2K1-2132407350aaENSP00000510066.1
 
Protein coding
A0A8I5QJP8 -GENCODE basic
ENST00000685172.1MAP2K1-2052389417aaENSP00000509604.1
 
Protein coding
A0A8I5KYB4 -GENCODE basic
ENST00000692683.1MAP2K1-2162350371aaENSP00000508437.1
 
Protein coding
B4DFY5 -GENCODE basic
ENST00000686347.1MAP2K1-2072209284aaENSP00000509027.1
 
Protein coding
A0A8I5QJC1 -GENCODE basic
ENST00000693150.1MAP2K1-2172133345aaENSP00000510309.1
 
Protein coding
CCDS92029A0A8I5KYS7 -GENCODE basic
ENST00000566326.1MAP2K1-2031432217aaENSP00000456438.1
 
Protein coding
H3BRW9 -GENCODE basicTSL:5
ENST00000692487.1MAP2K1-2154868252aaENSP00000509534.1
 
Nonsense mediated decay
A0A8I5QJL9 --
ENST00000691077.1MAP2K1-2124428252aaENSP00000509843.1
 
Nonsense mediated decay
A0A8I5QJL9 --
ENST00000684779.1MAP2K1-2041887227aaENSP00000508681.1
 
Nonsense mediated decay
A0A8I5KVF6 --
ENST00000687191.1MAP2K1-2084354No protein-
 
Retained intron
---
ENST00000688689.1MAP2K1-2101855No protein-
 
Retained intron
---
ENST00000687481.1MAP2K1-2091526No protein-
 
Retained intron
---
ENST00000425818.2MAP2K1-2021338No protein-
 
Retained intron
--TSL:5