Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: TOP1 ENSPTRG00000013498

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Description

DNA topoisomerase I [Source:VGNC Symbol;Acc:VGNC:10014]

Location

Chromosome 20: 42,638,762-42,733,323 forward strand.

Pan_tro_3.0:CM000334.4

About this gene

This gene has 2 transcripts (splice variants), 270 orthologues and 1 paralogue.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSPTRT00000025111.7	TOP1-201	2298	765aa	ENSPTRP00000023175.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A6D2WSH5 H2QKC9	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENSPTRT00000095829.1	TOP1-202	2160	719aa	ENSPTRP00000073829.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3S9X4	-

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Summary

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