Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: BACE1 ENSPTRG00000004324

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Description

beta-secretase 1 [Source:VGNC Symbol;Acc:VGNC:10433]

Location

Chromosome 11: 117,728,308-117,758,905 reverse strand.

Pan_tro_3.0:CM000325.3

About this gene

This gene has 5 transcripts (splice variants), 217 orthologues and 13 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSPTRT00000008034.5	BACE1-202	5865	501aa	ENSPTRP00000007415.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	H2Q4U8	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENSPTRT00000108420.1	BACE1-201	6381	401aa	ENSPTRP00000075727.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3SFC8 A0A6D2VY46	-
ENSPTRT00000099363.1	BACE1-204	1458	485aa	ENSPTRP00000066849.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3RQ90	-
ENSPTRT00000079456.1	BACE1-205	1404	467aa	ENSPTRP00000086261.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3TAH1	-
ENSPTRT00000079702.1	BACE1-203	837	278aa	ENSPTRP00000075348.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3SED1	-

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Summary

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