pyruvate kinase, muscle [Source:MGI Symbol;Acc:MGI:97591]
Pk-2, Pk-3, Pk3, Pkm2
Chromosome 9: 59,563,651-59,586,658 forward strand.
GRCm39:CM001002.3
This gene has 11 transcripts (splice variants), 310 orthologues, 1 paralogue and is associated with 9 phenotypes.
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|---|
| ENSMUST00000034834.16 | Pkm-201 | 2432 | 531aa | ENSMUSP00000034834.10 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS40659 | P52480 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P3: Where the APPRIS core modules are unable to choose a clear principal variant and there more than one of the variants have distinct CCDS identifiers, APPRIS selects the variant with lowest CCDS identifier as the principal variant. The lower the CCDS identifier, the earlier it was annotated. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P3,TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1, |
| ENSMUST00000163694.4 | Pkm-202 | 2041 | 531aa | ENSMUSP00000128770.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS57681 | P52480-2 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS ALT1: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that is conserved in at least three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT1,TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5, |
| ENSMUST00000213930.2 | Pkm-204 | 1017 | 232aa | ENSMUSP00000150578.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A0A1L1SU37 | TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENSMUST00000215660.2 | Pkm-207 | 743 | 187aa | ENSMUSP00000149206.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A0A1L1SQV8 | TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENSMUST00000215623.2 | Pkm-206 | 725 | 155aa | ENSMUSP00000150901.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A0A1L1SUV0 | TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENSMUST00000216857.2 | Pkm-209 | 718 | 102aa | ENSMUSP00000150188.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A0A1L1ST52 | TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENSMUST00000217038.2 | Pkm-210 | 625 | 184aa | ENSMUSP00000150509.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A0A1L1STV8 | TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENSMUST00000217353.2 | Pkm-211 | 582 | 176aa | ENSMUSP00000149983.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A0A1L1SSN6 | TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENSMUST00000216620.2 | Pkm-208 | 356 | 51aa | ENSMUSP00000151199.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A0A1L1SVH2 | TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENSMUST00000214571.2 | Pkm-205 | 2113 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1, | |
| ENSMUST00000213220.2 | Pkm-203 | 747 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2, |
